Disease genetics: Reporting on stability
|Originally posted:||11th September 2012: 2:30 pm|
|Last updated:||18th September 2012: 6:41 am|
|Public - anyone can view|
As the list of genetic variants that are implicated in disease gets longer, the challenge is to understand how they contribute to disease phenotypes. A recent study describes a high-throughput yeast system for detecting the effects of disease alleles on protein stability.