Protein level predictions 7 - Aggregation prediction
|Aggregation of proteins have been linked with diseases like neurogenerative diseases. Missense mutations can change the properties of proteins so that its tendency to aggregate increase. For this reason the predisposition of mutated proteins is evalutated by using the tools described in this group.
- Janita Thusberg and Mauno Vihinen. Pathogenic or Not? And If So, Then How? Studying the Effects of Missense Mutations Using Bioinformatics Methods. Hum Mutat.2009 May;30(5):703-14: doi:10.1002/humu.20938